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Acute myocarditis

MedGen UID:
102339
Concept ID:
C0155686
Disease or Syndrome
Synonyms: Acute Myocarditis; acute myocarditis; myocarditis, acute
SNOMED CT: Acute myocarditis (46701001)
 
Monarch Initiative: MONDO:0002815

Definition

The sudden onset of inflammation of heart muscle with myocellular necrosis; this is generally secondary to an infectious cause, and patients often have a recent history of a flu-like illness. [from NCI]

Professional guidelines

PubMed

Ammirati E, Moslehi JJ
JAMA 2023 Apr 4;329(13):1098-1113. doi: 10.1001/jama.2023.3371. PMID: 37014337
Lampejo T, Durkin SM, Bhatt N, Guttmann O
Clin Med (Lond) 2021 Sep;21(5):e505-e510. doi: 10.7861/clinmed.2021-0121. PMID: 34507935Free PMC Article
Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, Pedrotti P, Rimoldi OE, Schultheiss HP, Tschöpe C, Cooper LT Jr, Camici PG
Circ Heart Fail 2020 Nov;13(11):e007405. Epub 2020 Nov 12 doi: 10.1161/CIRCHEARTFAILURE.120.007405. PMID: 33176455Free PMC Article

Recent clinical studies

Etiology

Cristodulo R, Luoma-Overstreet G, Leite F, Vaca M, Navia M, Durán G, Molina F, Zonneveld B, Perrone SV, Barbagelata A, Kaplinsky E
Glob Heart 2023;18(1):41. Epub 2023 Aug 4 doi: 10.5334/gh.1254. PMID: 37547170Free PMC Article
Ammirati E, Raimondi F, Piriou N, Sardo Infirri L, Mohiddin SA, Mazzanti A, Shenoy C, Cavallari UA, Imazio M, Aquaro GD, Olivotto I, Pedrotti P, Sekhri N, Van de Heyning CM, Broeckx G, Peretto G, Guttmann O, Dellegrottaglie S, Scatteia A, Gentile P, Merlo M, Goldberg RI, Reyentovich A, Sciamanna C, Klaassen S, Poller W, Trankle CR, Abbate A, Keren A, Horowitz-Cederboim S, Cadrin-Tourigny J, Tadros R, Annoni GA, Bonoldi E, Toquet C, Marteau L, Probst V, Trochu JN, Kissopoulou A, Grosu A, Kukavica D, Trancuccio A, Gil C, Tini G, Pedrazzini M, Torchio M, Sinagra G, Gimeno JR, Bernasconi D, Valsecchi MG, Klingel K, Adler ED, Camici PG, Cooper LT Jr
JACC Heart Fail 2022 Oct;10(10):714-727. Epub 2022 Sep 7 doi: 10.1016/j.jchf.2022.06.013. PMID: 36175056
Ammirati E, Veronese G, Bottiroli M, Wang DW, Cipriani M, Garascia A, Pedrotti P, Adler ED, Frigerio M
Trends Cardiovasc Med 2021 Aug;31(6):370-379. Epub 2020 Jun 1 doi: 10.1016/j.tcm.2020.05.008. PMID: 32497572Free PMC Article
Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, Pedrotti P, Rimoldi OE, Schultheiss HP, Tschöpe C, Cooper LT Jr, Camici PG
Circ Heart Fail 2020 Nov;13(11):e007405. Epub 2020 Nov 12 doi: 10.1161/CIRCHEARTFAILURE.120.007405. PMID: 33176455Free PMC Article
Sagar S, Liu PP, Cooper LT Jr
Lancet 2012 Feb 25;379(9817):738-47. Epub 2011 Dec 18 doi: 10.1016/S0140-6736(11)60648-X. PMID: 22185868Free PMC Article

Diagnosis

Ammirati E, Moslehi JJ
JAMA 2023 Apr 4;329(13):1098-1113. doi: 10.1001/jama.2023.3371. PMID: 37014337
Lota AS, Hazebroek MR, Theotokis P, Wassall R, Salmi S, Halliday BP, Tayal U, Verdonschot J, Meena D, Owen R, de Marvao A, Iacob A, Yazdani M, Hammersley DJ, Jones RE, Wage R, Buchan R, Vivian F, Hafouda Y, Noseda M, Gregson J, Mittal T, Wong J, Robertus JL, Baksi AJ, Vassiliou V, Tzoulaki I, Pantazis A, Cleland JGF, Barton PJR, Cook SA, Pennell DJ, Garcia-Pavia P, Cooper LT Jr, Heymans S, Ware JS, Prasad SK
Circulation 2022 Oct 11;146(15):1123-1134. Epub 2022 Sep 26 doi: 10.1161/CIRCULATIONAHA.121.058457. PMID: 36154167Free PMC Article
Ammirati E, Buono A, Moroni F, Gigli L, Power JR, Ciabatti M, Garascia A, Adler ED, Pieroni M
Curr Cardiol Rep 2022 May;24(5):597-609. Epub 2022 Feb 24 doi: 10.1007/s11886-022-01680-x. PMID: 35201561Free PMC Article
Lampejo T, Durkin SM, Bhatt N, Guttmann O
Clin Med (Lond) 2021 Sep;21(5):e505-e510. doi: 10.7861/clinmed.2021-0121. PMID: 34507935Free PMC Article
Buttà C, Zappia L, Laterra G, Roberto M
Ann Noninvasive Electrocardiol 2020 May;25(3) Epub 2019 Nov 28 doi: 10.1111/anec.12726. PMID: 31778001Free PMC Article

Therapy

Ammirati E, Moslehi JJ
JAMA 2023 Apr 4;329(13):1098-1113. doi: 10.1001/jama.2023.3371. PMID: 37014337
Ammirati E, Veronese G, Bottiroli M, Wang DW, Cipriani M, Garascia A, Pedrotti P, Adler ED, Frigerio M
Trends Cardiovasc Med 2021 Aug;31(6):370-379. Epub 2020 Jun 1 doi: 10.1016/j.tcm.2020.05.008. PMID: 32497572Free PMC Article
Ammirati E, Cipriani M, Moro C, Raineri C, Pini D, Sormani P, Mantovani R, Varrenti M, Pedrotti P, Conca C, Mafrici A, Grosu A, Briguglia D, Guglielmetto S, Perego GB, Colombo S, Caico SI, Giannattasio C, Maestroni A, Carubelli V, Metra M, Lombardi C, Campodonico J, Agostoni P, Peretto G, Scelsi L, Turco A, Di Tano G, Campana C, Belloni A, Morandi F, Mortara A, Cirò A, Senni M, Gavazzi A, Frigerio M, Oliva F, Camici PG; Registro Lombardo delle Miocarditi
Circulation 2018 Sep 11;138(11):1088-1099. doi: 10.1161/CIRCULATIONAHA.118.035319. PMID: 29764898
Bracamonte-Baran W, Čiháková D
Adv Exp Med Biol 2017;1003:187-221. doi: 10.1007/978-3-319-57613-8_10. PMID: 28667560Free PMC Article
Kühl U, Schultheiss HP
Swiss Med Wkly 2014;144:w14010. Epub 2014 Oct 2 doi: 10.4414/smw.2014.14010. PMID: 25275335

Prognosis

Ammirati E, Moslehi JJ
JAMA 2023 Apr 4;329(13):1098-1113. doi: 10.1001/jama.2023.3371. PMID: 37014337
Lampejo T, Durkin SM, Bhatt N, Guttmann O
Clin Med (Lond) 2021 Sep;21(5):e505-e510. doi: 10.7861/clinmed.2021-0121. PMID: 34507935Free PMC Article
Ammirati E, Veronese G, Bottiroli M, Wang DW, Cipriani M, Garascia A, Pedrotti P, Adler ED, Frigerio M
Trends Cardiovasc Med 2021 Aug;31(6):370-379. Epub 2020 Jun 1 doi: 10.1016/j.tcm.2020.05.008. PMID: 32497572Free PMC Article
Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, Pedrotti P, Rimoldi OE, Schultheiss HP, Tschöpe C, Cooper LT Jr, Camici PG
Circ Heart Fail 2020 Nov;13(11):e007405. Epub 2020 Nov 12 doi: 10.1161/CIRCHEARTFAILURE.120.007405. PMID: 33176455Free PMC Article
Sagar S, Liu PP, Cooper LT Jr
Lancet 2012 Feb 25;379(9817):738-47. Epub 2011 Dec 18 doi: 10.1016/S0140-6736(11)60648-X. PMID: 22185868Free PMC Article

Clinical prediction guides

Ammirati E, Moslehi JJ
JAMA 2023 Apr 4;329(13):1098-1113. doi: 10.1001/jama.2023.3371. PMID: 37014337
Ammirati E, Veronese G, Bottiroli M, Wang DW, Cipriani M, Garascia A, Pedrotti P, Adler ED, Frigerio M
Trends Cardiovasc Med 2021 Aug;31(6):370-379. Epub 2020 Jun 1 doi: 10.1016/j.tcm.2020.05.008. PMID: 32497572Free PMC Article
Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, Pedrotti P, Rimoldi OE, Schultheiss HP, Tschöpe C, Cooper LT Jr, Camici PG
Circ Heart Fail 2020 Nov;13(11):e007405. Epub 2020 Nov 12 doi: 10.1161/CIRCHEARTFAILURE.120.007405. PMID: 33176455Free PMC Article
Filigheddu MT, Górgolas M, Ramos JM
Med Clin (Barc) 2017 Feb 9;148(3):125-131. Epub 2016 Dec 16 doi: 10.1016/j.medcli.2016.10.038. PMID: 27993415
Sagar S, Liu PP, Cooper LT Jr
Lancet 2012 Feb 25;379(9817):738-47. Epub 2011 Dec 18 doi: 10.1016/S0140-6736(11)60648-X. PMID: 22185868Free PMC Article

Recent systematic reviews

Monda E, Bakalakos A, Cannie D, O'Mahony C, Syrris P, Kaski JP, Limongelli G, Elliott PM
JACC Heart Fail 2024 Jun;12(6):1101-1111. Epub 2024 Apr 3 doi: 10.1016/j.jchf.2024.02.012. PMID: 38573261
Ishisaka Y, Watanabe A, Aikawa T, Kanaoka K, Takagi H, Wiley J, Yasuhara J, Kuno T
Int J Cardiol 2024 Jan 15;395:131401. Epub 2023 Sep 28 doi: 10.1016/j.ijcard.2023.131401. PMID: 37774926
Yao Q, Zhan S
Ital J Pediatr 2023 Mar 13;49(1):30. doi: 10.1186/s13052-023-01423-w. PMID: 36915162Free PMC Article
Zuin M, Rigatelli G, Bilato C, Porcari A, Merlo M, Roncon L, Sinagra G
Can J Cardiol 2023 Jun;39(6):839-844. Epub 2022 Dec 12 doi: 10.1016/j.cjca.2022.12.003. PMID: 36521730Free PMC Article
Sawalha K, Abozenah M, Kadado AJ, Battisha A, Al-Akchar M, Salerno C, Hernandez-Montfort J, Islam AM
Cardiovasc Revasc Med 2021 Feb;23:107-113. Epub 2020 Aug 18 doi: 10.1016/j.carrev.2020.08.028. PMID: 32847728Free PMC Article

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